PROBLEM TO BE SOLVED: To provide compounds for the modulation of blood uric acid levels, and for the treatment of gout or hyperuricemia.SOLUTION: This invention relates to a compound expressed by the formula (I), where Ra and Rb are selected from H, halogen, C1 to C6 alkyl, or the like； M is H, C1-3 alkyl or the like； X1 is N, CH, C(halogen) or the like； X2 is N or CH； X3 is N, CH, C(halogen) or C(C1-C4 alkyl)； and X4 is N or CH, wherein at least one of X1 to X4 is N； Y1 is N or CR1； Y2 is N or CR2； R1 is H, CF3, CH3, OCH3, F or Cl； and R2 is H, methyl, ethyl, propyl, isopropyl, tert-butyl, cyclopropyl, cyclobutyl, CF3, OH, OCH3, ethoxy, or the like.【課題】血清尿酸値の調節、あるいは、痛風または高尿酸血症の処置のための、化合物の提供。【解決手段】式（Ｉ）で表される化合物。（Ｒａ及びＲｂはＨ、ハロゲン、Ｃ１－Ｃ６アルキル等；ＭはＨ、Ｃ１－３アルキル等；Ｘ１はＮ、ＣＨ、Ｃ（ハロゲン）等；Ｘ２はＮ又はＣＨ；Ｘ３はＮ、ＣＨ、Ｃ（ハロゲン）又はＣ（Ｃ１－Ｃ４アルキル）；Ｘ４はＮ又はＣＨ；Ｘ１～Ｘ４の少なくとも１つはＮ；Ｙ１はＮ又はＣＲ１；Ｙ２はＮ又はＣＲ２；Ｒ１はＨ、ＣＦ３、ＣＨ３、ＯＣＨ３、Ｆ又はＣｌ；Ｒ２はＨ、メチル、エチル、プロピル、イソプロピル、ｔｅｒｔ－ブチル、シクロプロピル、シクロブチル、ＣＦ３、ＯＨ、ＯＣＨ３、エトキシ等）【選択図】なし
