OH, Hee Sook,오희숙,JUNG, Jae Hyuk,정재혁,JEON, Ji Young,전지영,JANG, Sun Young,장선영,HA, Tae Hee,하태희
申请号：
KRKR2020/003850
公开号：
WO2020/204426A1
申请日:
2020.03.20
申请国别(地区):
KR
年份:
2020
代理人:
摘要：
One embodiment relates to: a crystal form of an acid addition salt of N-(3-(2-(4-(4-methylpiperazine-1-yl)phenylamino)puro[3,2-d]pyrimidine-4-yloxy)phenyl)acrylamide； and a pharmaceutical composition comprising same. The crystal form can be easily used in the preparation of a pharmaceutical composition comprising same as an active ingredient.Selon un mode de réalisation, la présente invention concerne une forme cristalline d'un sel d'addition d'acide de N-(3-(2-(4-(4-méthylpipérazine-1-yl)phénylamino)puro[3,2-d]pyrimidine-4-yloxy)phényl)acrylamide et une composition pharmaceutique comprenant ladite forme cristalline. La forme cristalline peut être facilement utilisée pour la préparation d'une composition pharmaceutique la comprenant en tant que principe actif.일 양상은 N-(3-(2-(4-(4-메틸피페라진-1-일)페닐아미노)퓨로[3,2-d]피리미딘-4-일옥시)페닐)아크릴아마이드의 산부가염의 결정형 및 이를 포함하는 약학적 조성물에 관한 것이다. 상기 결정형은 이를 유효 성분으로 포함하는 약학적 조성물의 제조에 용이하게 이용될 수 있다.
