SolutionsThe interleukin -6 (the IL-6) and/or IL-6 receptor or the part of that, it connects to person IL-6 desirably or, being the chemical compound which includes the structure which is that competition medicine at least, the damage, destruction of the endothelium, the damage of the endothelium or increase of risk of destruction or the chemical compound which removes IL-6 from the solution in order to produce the medicine for remedy or prevention of the disease which is selected from immunity obstacle other than chronic joint riumachi, and the group which consists of those combinations, or, on the cell surface, or, in the said solution, use of the chemical compound which at least cuts off the function of IL-6 of one or more.【解決手段】インターロイキン-6(IL-6)及び/またはIL-6受容体またはその部分、好ましくはヒトIL-6に結合するかその拮抗剤である構造体を少なくとも含む化合物であって、内皮の損傷、破壊、内皮の損傷もしくは破壊のリスクの増加または慢性関節リウマチ以外の免疫障害、及びそれらの組み合わせよりなる群から選択される疾病の治療または予防用の医薬を製造するための溶液からIL-6を除去する化合物、あるいは、細胞表面上、または、該溶液中で、少なくとも1つ以上のIL-6の機能を遮断する化合物の使用。
