Open Monoclonal Technology, Inc.;WuXi Biologics (Cayman) Inc.
发明人:
Zheng, Yong,Li, Jing,Chen, Zhisheng
申请号:
AU2016305697
公开号:
AU2016305697A1
申请日:
2016.08.11
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present disclosure provides monoclonal antibodies against protein programmed cell death 1 (PD-1), which can block the binding of PD-1 ligands to PD-1, and therefore block the inhibitory function of PD-1 ligands on PD-1 expressing T cells. The antibodies of disclosure provide very potent agents for the treatment of multiple cancers via modulating human immune function.