A use of an extract of Zingiber zerumbet for manufacturing a drug of diabetic retinopathy is disclosed. The extract of Zingiber zerumbet is administered to a subject in need thereof to improve diabetic retinopathy of the subject in need.一種紅球薑萃取物之用途,係應用於製備改善糖尿病視網膜病變的藥物,該紅球薑萃取物係投予一所需生物體,以改善該所需升物體之糖尿病視網膜病變現象。