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Methods and devices for non-invasive cerebral and systemic cooling
专利权人:
Denise Barbut
发明人:
Denise Barbut,Allan Rozenberg,John K. Hoffman
申请号:
US12101933
公开号:
US08480723B2
申请日:
2008.04.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A method for cerebral and systemic cooling by providing a nebulized liquid having a boiling point of 38-300° C. The nebulized liquid is delivered as a mist or a spray via the nasal and/or oral cavities of a patient. The mist causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis. Compositions and medical devices for cerebral and systemic cooling are also provided. Cooling assemblies, and methods of use, are also provided that include flexible balloon assemblies that are inserted to various locations in a patients body. The flexible balloons are then infused with a liquid having a temperature between about −20° C. and about 37° C. The flexible balloon assemblies can be inserted into the nasal cavity, oral cavity, throat, stomach, and other locations to effect cerebral cooling.
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