Lei Guo,Di Xu,See-Lok Ho,Chung-Yan Poon,Olivia T. W. Ng,Hung Wing Li,Ken K. L. Yung,Daniel W. J. Kwong,Ricky M. S. Wong
申请号：
US14231724
公开号：
US09403794B2
申请日:
2014.03.31
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention is in the field of pharmaceuticals and chemical industries. In particular, the present invention relates to methods for labeling, imaging and detecting the beta-amyloid (Aβ) peptides, oligomers, and fibrils in vitro by using carbazole-based fluorophores. A further aspect of the present invention relates to a method of reducing and preventing aggregation of beta-amyloid peptides for Alzheimers disease (AD) as well as of treating and/or preventing Alzheimers disease by using carbazole-based fluorophores.
