An ophthalmoscope includes an illumination assembly having a light source disposed along an illumination axis and an imaging assembly configured for delivering an image to an imaging device. Each of the imaging and illumination assemblies are disposed in an instrument housing, the ophthalmoscope being configured for attachment to an electronic imaging device and in which the imaging assembly produces a field of view of about 40 degrees to permit more comprehensive eye examinations to be reliably conducted. In at least one version, a portable electronic device, such as a smart device, can be coupled to the instrument or configured to wirelessly receive images therefrom.