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VARIANT ACTRIIB PROTEINS AND USES THEREOF
专利权人:
Acceleron Pharma Inc.
发明人:
Ravindra Kumar,Asya Grinberg,Erik M. Vogan
申请号:
US16340048
公开号:
US20200055919A1
申请日:
2017.10.05
申请国别(地区):
US
年份:
2020
代理人:
摘要:
In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of red blood cells or a tissue, such as bone, cartilage, muscle, fat, and/or neuronal tissue. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRIIB protein and/or an ActRIIB ligand.
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http://www.ckcest.cn/home/
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