Gurnett-Bander Anne,Arrecubieta Carlos,Lowy Israel
申请号:
NZ71451613
公开号:
NZ714516A
申请日:
2013.03.01
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Discloses an isolated antibody or antigen-binding fragment thereof that specifically binds to Clostridium difficile toxin B, comprising: the HCDR1 , HCDR2 and HCDR3 contained within a HCVR amino acid sequence of SEQ ID NO: 274; and the LCDR1 , LCDR2 and LCDR3 contained within a LCVR amino acid sequence of SEQ ID NO: 282, wherein the sequences are as defined in the complete specification. Further discloses related uses to treat a patient suffering from a Clostridium difficile-associated condition or disease.