595941 Discloses the use of dimethyl fumarate in the preparation of a medicament for the treatment of a subject having multiple sclerosis, wherein the medicament is formulated for administration of a first dose of the medicament for a first dosing period and administration of a second dose of the medicament for a second dosing period, wherein the first does of the medicament comprises 120mg dimethyl fumarate formulated for oral administration two or three times per day for the first dosing period, and wherein the second dose of comprises 240mg dimethyl fumarate and is formulated for oral administration two times per day (BID) for the second dosing period.
