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6-ALKENYL AND 6-PHENYLALKYL SUBSTITUTED 2-QUINOLINONES AND 2-QUINOXALINONES AS POLY(ADP-RIBOSE) POLYMERASE INHIBITORS
专利权人:
Jerome Emile Georges Guillemont;Walter Boudewijn Leopold Wouters;Maria Victorina Francisca Somers;Jacobus Alphonsus Josephus Van Dun;Dominique Jean-Pierre Mabire
发明人:
Dominique Jean-Pierre Mabire,Jerome Emile Georges Guillemont,Jacobus Alphonsus Josephus Van Dun,Maria Victorina Francisca Somers,Walter Boudewijn Leopold Wouters
申请号:
US13284110
公开号:
US20120046274A1
申请日:
2011.10.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides compounds of formula (I) and compounds of formula (VII-a) as well as pharmaceutical compositions comprising said compounds and their use as PARP inhibitorswherein n, R1, R2, R3, R4, R5, R6, R7, Re, Rd and X have defined meanings.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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