A gastrointestinal balloon system includes a gastrointestinal balloon and a valve located within the gastrointestinal balloon. The valve is configured to allow fluid flow into and out of the gastrointestinal balloon. The valve includes a string coupled to the valve, the string having a loop on a proximal end and a catheter having a lumen. The lumen is configured to receive a grasping tool. The grasping tool extends out a distal end of the catheter for grabbing the loop to align the catheter with the valve. The valve may be a series of self-sealing two-way valves, a check valve, or two-way valve. A method of using a valve in a gastrointestinal balloon is also described.