LU, JINGWEI,YANG, ZHIYUAN,LIU, CHENG,LIU, HONG,XU, YIYANG,YAN, SU,CHAN, VIVIEN WAI-FAN,HORAN, LUCAS
申请号:
CA3001137
公开号:
CA3001137A1
申请日:
2016.10.21
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.