Disclosed is a system that includes a signal acquisition circuit to acquire a cuff pressure signal using an inflatable cuff, and to generate an oscillometric signal from the cuff pressure signal. The system also includes a user interface to enter one or more patient-specific detection threshold values, a memory to store the cuff pressure signal, the oscillometric signal, and the one or more patient-specific detection threshold values. The system also includes a microprocessor operatively coupled to the signal acquisition circuit, the user interface, and the memory. The microprocessor includes at least one algorithm to use the cuff pressure signal, the oscillometric signal, and the entered one or more patient-specific detection threshold values to calculate patient-specific readings of at least one of mean arterial pressure, systolic blood pressure and diastolic blood pressure. Related apparatus, systems, methods and/or articles are described.