#$%^&*AU2015200600B220170420.pdf#####H:szp Interwoven NRPortbl DCC SZP 7390874 1docx-21/01/2015 ABSTRACT Cell-penetrating peptides useful for targeting a therapeutic compound to a selected mammalian tissue, methods for their identification, methods of forming conjugate compounds containing such peptides, and conjugates formed thereby are disclosed. The cell-penetrating peptides are 8 to 30 amino acid residues in length and consist of subsequences selected from the group consisting of RXR, RX, RB, and RBR； where R is arginine, B is -alanine, and each X is independently -C(O)-(CHR1 )n-NH-, where n is 4-6 and each RI is independently H or methyl, such that at most two Rl,s are methyl. In one embodiment, X is a 6-aminohexanoic acid residue.2/27 0 -C 0 -~M: z 0 z zp Iz +Za 0) 0 0) 0 CL z yz Iz +Z Nl
