A method of image processing, including:(a) calculating at least one pixel color feature (PCF) value for each pixel in a color medical image to generate a set of PCF data and(b) filtering the PCF data with at least one spatial adaptive bandpass filter (ABPF) to sort the pixels into physiologically significant regionswherein the at least one PCF value for at least one pixel depends on at least 2 color components of the medical image.