The present invention is an implantable, self-adhering mesh prosthesis (300, 400) for repairing animal tissue. In one embodiment, the prosthesis comprises a sheet of mesh material comprising first (304) and second opposing major surfaces, and has a plurality of creases that intersect at an intersection point. The creases of the sheet of mesh material provides the prosthesis with a three-dimensional shape. Furthermore, the prosthesis further comprises two or more adhesive lines (320, 321, 322, 323, 420, 421, 422, 423, 424) on the first major surface (304), wherein the adhesive lines (320, 321, 322, 323, 420, 421, 422, 423, 424) are substantially parallel to an adhesive line axis. The adhesive lines (320, 321, 322, 323, 420, 421, 422, 423, 424) are distributed unevenly over the first major surface (304) such that the distance between a first adhesive line (320, 420) to the intersection point differs from the distance between a second adhesive line (323, 423) to the intersection point.