A vertical plant growing system may include a vertical plant stand having a central lighting array and defining a plurality of guided airflows, the plant stand being coupled to a heating, ventilation, and air conditioning (HVAC) system. The HVAC system and plant stand may be operable in a plurality of airflow modes, ranging from about 35 degrees Fahrenheit (to inhibit insect growth) to about 98 degrees Fahrenheit (to kill mold). Accordingly, systems and methods of the present disclosure may facilitate or enhance organic growing methods, e.g., for flowering plants.