Diacuerpos monovalent biespecificos that are able to bind to CD3 and CD123 and Use thereof

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专利权人:

INC.;MACROGENICS

发明人:

BONVINI, EZIO,JOHNSON, LESLIE, S,HUANG, LING,MOORE, PAUL, A,CHICHILI, GURUNADH, REDDY,ALDERSON, RALPH, FROMAN

申请号：

CR20160108

公开号：

CR20160108A

申请日:

2016.03.04

申请国别(地区):

CR

年份:

2016

代理人:

摘要：

The current invention is aimed at two celestial bodies with optimized CD123 x CD3 unit sequence, which can be combined with CD123 and CD3 at the same time, and use these two celestial bodies in the treatment of hematological malignancies.La presente invención se dirige a los diacuerpos biespecíficos monovalentes de secuencia optimizada CD123 x CD3 que son capaces de unión simultánea a CD123 y CD3, y a los usos de tales diacuerpos en el tratamiento de malignidades hematológicas.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/