Jennifer E. Woodell-May;Jacy C. Hoeppner;Joel C. Higgins
发明人:
Joel C. Higgins,Jennifer E. Woodell-May,Jacy C. Hoeppner
申请号:
US12394723
公开号:
US10106587B2
申请日:
2009.02.27
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods and compositions generating and using an interleukin-1 receptor antagonist (IL-1ra)-rich solution. Methods for generating and isolating interleukin-1 receptor antagonist include incubating a liquid volume of white blood cells and platelets with polyacrylamide beads to produce interleukin-1 receptor antagonist. The interleukin-1 receptor antagonist is isolated from the polyacrylamide beads to obtain the solution rich in interleukin-1 receptor antagonist. Methods for treating a site of inflammation in a patient include administering to the site of inflammation the solution rich in interleukin-1 receptor antagonist.