Общество с ограниченной ответственностью "НИАРМЕДИК ПЛЮС" (RU)
发明人:
Макаров Вадим Альбертович (RU),Нестеренко Владимир Георгиевич (RU),Болгарин Роман Николаевич (RU),Новоселова Елена Александровна (RU)
申请号：
RU2015144872
公开号：
RU2015144872A
申请日:
2015.10.20
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
The invention relates to novel pyrimidyl-di(diazaspiro-alkane) derivatives of formula (I) or a pharmaceutically acceptable acid additive salt thereof. The compounds exhibit a wide spectrum of antiviral activity against herpes virus, human immunodeficiency virus, papillomavirus, and hepatitis virus. The invention also relates to use of the compounds of formula (I), a method for preparing thereof, and a method for treating by using the claimed compounds. The general formula is: (I) A represents pyrimidine-4,6-diyl or pyrimidine-2,4-15 diyl that can comprise H, NO2, CHO, OH, OAlk, halogen, NH(Alk), or N(Alk)2 as a substituent Hal represents chlorine or bromine Alk is a linear or branched substituent having 1 to 4 carbon atoms.
