POLYPEPTIDES AYANT UN EFFET ANTAGONISTE SUR LA SIGNALISATION WNT DANS DES CELLULES TUMORALES

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

ZINZALLA, VITTORIA,KUENKELE, KLAUS-PETER,BUYSE, MARIE-ANGE,CROMIE, KAREN,STAELENS, STEPHANIE,STRUBBE, BEATRIJS

申请号：

CA3060401

公开号：

CA3060401A1

申请日:

2018.05.30

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The invention provides novel LRP5-binding polypeptides, and more specificallynovel LRP5-binding immunoglobulinsingle variable domain constructs which can inhibit Wnt signaling pathways.The invention also relates to specific sequences of suchpolypeptides, methods of their production, and methods of using them,including methods of treatment of diseases such as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/