A cradle for positioning an anatomical portion of a patient during treatment includes a plurality of expandable fluid chambers and a pressure regulator configured to supply fluid to and withdraw fluid from each of the fluid chambers. A system for positioning an anatomical portion of a patient during treatment includes the aforementioned cradle and a control unit configured to control the pressure of each of the fluid chambers. A method for positioning an anatomical portion of a patient during treatment comprises the steps of placing the anatomical portion in the aforementioned cradle and adjusting the pressure of each of the fluid chambers to hold the anatomical portion in a desired position.