It refers to the compound of formula (I), wherein R1 is h, hydroxi, halogeno, Ciano, C (o) (C1-6 tar),R2 is, among other things, h, hydroxi, halogeno, Ciano, NHC (o) (C1-6 hydrocarbon),Among other things, R3 is h, hydroxi, C (o) (C1-6 hydrocarbon),Cyanogen, halogen, etc.； R4 is a kind of optional phenyl, which is replaced by one, two or three times with a kind of halogenated atom in identification or different ways； X and y are CH2； n is 0.1.2. They are the preferred compounds: 1 - [4 - (6-methyl-3-fenilimidazo [1, 2-B] piridazin-2-il] fenil] - cyclobutamine； 2 - [4 - (1-amino-butil) fenil] - 3-fenilimidazo [1, 2-B] - piridazin-6-carboxillico； among other things, they are also related to the process for the manufacture of these compounds and a potent compound. These compounds are useful for the treatment of breast cancerSE REFIERE A COMPUESTOS DE FORMULA (I) DONDE: R1 ES H, HIDROXI, HALOGENO, CIANO, C(O)(ALQUILO C1-6), ENTRE OTROS； R2 ES H, HIDROXI, HALOGENO, CIANO, NHC(O)(ALQUILO C1-6), ENTRE OTROS； R3 ES H, HIDROXI, C(O)(ALQUILO C1-6), CIANO, HALOGENO, ENTRE OTROS； R4 ES FENILO OPCIONALMENTE SUSTITUIDO UNA, DOS O TRES VECES, EN FORMA IDENTICA O DIFERENTE, CON UN ATOMO DE HALOGENO； X E Y ES CH2； n ES 0,1,2. SON COMPUESTOS PREFERIDOS: 1-[4-(6-METIL-3-FENILIMIDAZO[1,2-b]PIRIDAZIN-2-IL)FENIL]-CICLOBUTAMINA； ACIDO 2-[4-(1-AMINOCICLOBUTIL)FENIL]-3-FENILIMIDAZO[1,2-b]-PIRIDAZIN-6-CARBOXILICO； ENTRE OTROS.SE REFIERE TAMBIEN A UN PROCESO PARA PARA LA FABRICACION DE DICHOS COMPUESTOS Y A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON UTILES PARA EL TRATAMIENTO DE CANCER DE MAMAS
