醫藥組合物在製備治療急性腎臟損傷之藥物的用途农业专利-农业学术服务平台

发明人:: KUO, TZONG-FU,郭宗甫,LUO, YU-SIANG,罗玉翔,羅玉翔,CHAN, MING-YUN,詹明澐,SHEU, SHI-YUAN,许世源,許世源,TAI, YU-TING,戴裕庭,CHUANG, MING-HSI,庄明熙,莊明熙,LIN, PO-CHENG,林珀丞,CHOU, HSIEN-MIN,周宪民,周憲民

摘要：: The present invention relates to a pharmaceutical composition for treating an acute kidney injury, the pharmaceutical composition comprises stem cells and a platelet-rich fibrin (PRF) releasing solution； wherein the stem cells are embryonic stem cells, adult stem cells, or induced pluripotent stem cells, the platelet-rich fibrin releasing solution contains at least one growth factor selected from TGF-[beta]1 (Transforming growth factor-beta1), VEGF (Vascular endothelial growth factor), PDGF (Platelet-derived growth factor), BMP (Bone morphogenetic protein), PF4 (Platelet factor 4), IL (Interleukin), EGF (Epidermal growth factor), FGF (Fibroblast growth factor), NGF (Nerve growth factor), and IGF (Insulin-like growth factor).本發明係關於一種用於治療急性腎臟損傷之醫藥組合物，該醫藥組合物包括幹細胞及一富含血小板纖維蛋白(Platelet-rich fibrin,PRF)釋放液；其中，該幹細胞係胚胎幹細胞、成體幹細胞、或誘導型多能幹細胞，該富含血小板纖維蛋白釋放液係含有從TGF-β1(Transforming growth factor-betal)、VEGF(Vascular endothelial growth factor)、PDGF(Platelet-derived growth factor)、BMP(Bone morphogenetic protein)、PF4(Platelet factor 4)、IL(Interleukin)、EGF(Epidermal growth factor)、FGF(Fibroblast growth factor)、NGF(Nerve growth factor)、及IGF(Insulin-like growth factor)中所選出之至少一種生長因子。