Compositions comprising: - saligenin or derivatives thereof or Salix sspextracts containing from 10 to 50% ofsaligenin; - substantially pure andrographolide or andrographolide enrichedAndrographis paniculata extract containing from 5 to30% of andrographolide; - optionally N-acetyl-glucosamine and/or - glucuronicacid or glucuronolactone.