GILES-KOMAR JILL,KNIGHT DAVID M,SCALLON BERNARD,SHEALY DAVID,HEAVNER GEORGE
申请号：
NO20030620
公开号：
NO333378B1
申请日:
2003.02.07
申请国别(地区):
NO
年份:
2013
代理人:
摘要：
Disclosed is an antibody, or an antigen-binding fragment thereof, having three heavy chain complementary determining regions (CDRs) and three light chain CDRs, wherein each heavy chain CDR comprises the amino acid sequence of the corresponding heavy chain CDR of mAb TNV148 as described in Figure 4； and each light chain CDR of mAb TNV 148 as described in Figure 5.Foreliggende oppfinnelse gjelder minst et nytt anti-TNF-antistoff og omfatter isolerte nukleinsyrer som koder for minst et anti-TNF-antistoff, TNF, vektorer, vertsceller, transgene dyr eller planter ogfremgangsmåter for fremstilling og anvendelse derav.
