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2、 Individuals infected with hepatitis B virus (VHb) using a combination of appropriate drugs (PVO) and at least one additional antiretroviral therapy
专利权人:
AICURIS GMBH & CO. KG
发明人:
DR. SLOOT, WILLEM,DR. MENNE, STEPHAN,DR. PFAFF, TAMARA,DR. ADDY, IBIRONKE,DR. URBAN, ANDREAS,DR. PAULSEN, DANIELA
申请号:
ARP180102551
公开号:
AR112796A1
申请日:
2018.09.07
申请国别(地区):
AR
年份:
2019
代理人:
摘要:
It refers to a combination therapy for individuals infected with VHb using ovis (PPVO) and at least one additional antiretroviral drug (such as ribose inhibitor). It's like entecavir. The current combination of methods and products is safe and appropriate for patients with long-term infection with Hexabromodiphenyl. 1. Claim 1: an ingredient composed of parathion virus selected from the group, including: optional inactive parathion virus (PVO) virgins and / or active fragments thereof,And / or nucleic acid or carrier of synthetic nucleic acid molecule, representing PVO and / or at least its active part and / or cell, including toxicity of PVO or its fragment and / or its nucleic acid carrier and / or synthetic nucleic acid molecule representing PVO and / or at least one active part Among them,It is used in combination with at least one different antiretroviral drug for the treatment of people infected with hepatitis B virus (VHb). Requirement 4: according to any one of requirements 1 to 3 selected from the strain group, the components including PVO used in combination with at least one different antiretroviral drug for the treatment of people with hepatitis B (VHb) PPVO includes NZ2, nz7, NZ10, d701, OV / 20, OV / 7, OV / C2, OV / mi-90, OV Torino, SA00, bo29, orf11,ECA ORF green 155 and / or ECA ORF green 176 or the parasite virus (Ovis) strain ORF related to biological classification. Claim 6: a component containing PVO for the treatment of an infected person in combination with at least one different antiretroviral drug, VHb according to any one claims 1 to 5, A group of drugs containing nucleoside / nucleoside analogues as the principle of activity includes tenor's virus, dinitro sodium (TDF),Tenofovir-Alafenamid(TAF),Entercavir, lamivudina, telbivudina, adefovir, emtricitabina and / or clevudina.Se refiere a terapias de combinación de individuos infectados con VHB usando un Parapoxvirus ovis (PPVO) y al menos un fármaco antivírico adicional, por ejemplo, inhibi
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