Vaccine compositions comprising Tryptophan 2,3-dioxygenase or fragments thereof

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专利权人:

Herlev Hospital

发明人:

Andersen, Mads Hald

申请号：

AU2015317446

公开号：

AU2015317446A1

申请日:

2015.09.15

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The invention relates to prophylaxis and therapy of cancer. In particular there is provided a protein Tryptophan2,3-dioxygenase (TDO) or peptide fragments here of that are capable of eliciting anti-cancer immune responses. Specifically, the invention relates to the use of TDO or peptides derived thereof or TDO specific T-cells for treatment of cancer. The invention thus relates to an anti-cancer vaccine which optionally may be used in combination with other immunotherapies and to TDO specific T-cells adoptively transferred or induced

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