B型肝炎ウィルスの抑制に用いるベニクスノキタケシクロヘキサンケトン化合物

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专利权人:

國鼎生物科技股▲ふん▼有限公司

发明人:

劉 勝勇,温 武哲,郭 茂田

申请号：

JP2007203975

公开号：

JP5085222B2

申请日:

2007.08.06

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

The present invention relates to a compound of Antrodia camphorata used to inhibit HBV, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone which is isolated from Antrodia camphorata, and its use in inhibiting HBV effectively. The cyclohexenone compound according to the present invention showed cytotoxicity on HBV-secreting human hepatoma cell line HepG2 2.2.15, decreased synthesis of HBV particles, further inhibited synthesis of HbsAg and HbeAg effectively to achieve the goal of HBV inhibition.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/