Yao-Ling Qiu,Hui Cao,Wei Li,Jorden Kass,Xuri Gao,Xiaowen Peng,Meizhong Jin,Yat Sun Or
申请号:
US15088517
公开号:
US20160289212A1
申请日:
2016.04.01
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof:X-A-Y-Z-L-R1 (I)which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.