Leonard G. Presta;Anan Chuntharapai;Timothy Stewart;Jin K. Kim
发明人:
Anan Chuntharapai,Jin K. Kim,Leonard G. Presta,Timothy Stewart
申请号：
US13476878
公开号：
US20120244148A1
申请日:
2012.05.21
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates generally to the generation and characterization of neutralizing anti-IFN-α monoclonal antibodies with broad reactivity against various IFN-α subtypes. The invention further relates to the use of such anti-IFN-α antibodies in the diagnosis and treatment of disorders associated with increased expression of IFN-α, in particular, autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE).
