COMPOSITIONS AND METHODS FOR BORON NEUTRON CAPTURE THERAPY

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专利权人:

发明人:

Satish S. Jalisatgi,Marion Frederick Hawthorne

申请号：

US15120429

公开号：

US20170007700A1

申请日:

2015.02.23

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Provided herein are compositions and methods for boron neutron capture therapy. In particular, the disclosure relates to therapy using liposomal Na3[1-(2′-B10H9)-2-NH3B10H8] and K[nido-7-CH3(CH2)15-7,8-C2B9H11] sources. A composition for boron neutron capture therapy, comprising a liposome having an aqueous core and an encapsulating bilayer, wherein the aqueous core comprises Na3[1-(2′-B10H9)-2-NH3B10H8] (TAC) and the encapsulating bilayer comprises K[nido-7-CH3(CH2)15-7,8-C2B9H11] (MAC) is also provided.

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