The invention encompasses combinations of bioactive glass composition and potassium salts that are useful in conjunction with delivery agent such as, for example, toothpastes, mouthwashes, and oral gels. In certain embodiments, the compositions of the invention form a rapid and continuous reaction with body fluids (e.g., saliva) to promote the immediate and long-term release of Ca and P ions to produce a stable crystalline layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.本發明係涵蓋生物活性玻璃組成物及鉀鹽之組合物,其可用於與傳遞劑例如牙膏、漱口水及口內凝膠結合。在特定的實施例中,本發明之組成物與體液(例如唾液)形成快速及持續的反應,促使Ca和P離子立即和長時間的釋放,而產生一沉積在牙本質小管上及其內之安定的結晶層,供立即和長期降低牙本質過敏和牙齒表面再礦化。