肝細胞腫瘤（ＨＣＣ）之治療农业专利-农业学术服务平台

发明人:: ABADA, PAOLO BENJAMIN,阿贝达　保罗　班哲明,阿貝達　保羅　班哲明,CHANG, SHAO-CHUN,张　小谆,張　小諄,HSU, YANZHI,徐　延希,YANG, LING,杨玲,楊玲,阿贝达保罗班哲明,阿貝達保羅班哲明,张小谆,張小諄,徐延希

摘要：: The invention provides for a human antibody that binds to human vascular endothelial growth factor receptor 2, preferably ramucirumab, for the treatment of hepatocellular carcinoma in patients having levels of alpha-fetoprotein (AFP) of 1.5 ULN or greater, and as a predictive method for the treatment of HCC in patients having AFP levels of 1.5 x ULN or greater.本發明提供結合至人類血管內皮生長因子受體2之人類抗體，較佳雷莫蘆單抗(ramucirumab)，其用於治療具有1.5 ULN或更高α-胎兒蛋白(AFP)含量之患者之肝細胞癌，並作為用於治療具有1.5×ULN或更高之AFP含量之患者之HCC之預測性方法。