4,5-Dihydro- [1,2,4] triazolo [4,3-F] pteridines useful as inhibitors of protein kinase PLK1 for the treatment of proliferative diseases

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专利权人:

バーテックス ファーマシューティカルズ インコーポレイテッド

发明人:

ジャン－ダミアン・シャリエール,デイビッド・ケイ,ロナルト・クネフテル,ジャン-ダミアン・シャリエール

申请号：

JP2009505472

公开号：

JP5313875B2

申请日:

2007.04.12

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The present invention relates to compounds useful as inhibitors of protein kinase, represented by Structural Formula (I): wherein the variables in Structural Formula (I) are as described herein. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

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