The invention relates to biotechnology. The exenatide analogue with the formula H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-As-Leu-Ser-Lys-Gln-Glu-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro- Pro-Ser-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-Gly-OH is presented. The invention allows treating and taking preventive measures against diabetes mellitus as well as treating and taking preventive measures against type 2 diabetes mellitus complications, such as diabetic neuropathy, muscular dystrophy and endotheliopathy.