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Combinations for the treatment of diseases associated with cell proliferation.
专利权人:
Boehringer Ingelheim International GmbH
发明人:
Munzert, Gerd,Steegmaier, Martin,Baum, Anke
申请号:
DK10184338
公开号:
DK2275107T3
申请日:
2005.08.09
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The present invention relates to a pharmaceutical composition for the treatment of diseases which involve cell proliferation. The invention also relates to a method for the treatment of said diseases, comprising co-administration of a compound 1 of Formula (I) wherein the groups L, R 1 , R 2 , R 3 , R 4 and R 5 have the meanings given in the claims and specification, optionally in form of its tautomers, racemates, enantiomers, diastereomers and the mixtures thereof and optionally in form of the pharmacologically acceptable acid addition salts, solvates, hydrates, polymorphs, physiologically functional derivatives or prodrugs thereof and of an effective amount of an active compound 2 and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of a compound 1 of Formula (I) and of an effective amount of an active compound 2 and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.
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