The Board of Trustees of the Leland Stanford Junior University
发明人:
ASHLEY, Euan A.,PEREZ, Marco V.
申请号:
EP14862291
公开号:
EP3068783A4
申请日:
2014.11.13
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Methods of treating individuals for heart failure are disclosed. In particular, the invention relates to methods of treating individuals for heart failure with agonists of hypocretin receptor 2. The invention further relates to the use of genetic analysis of the single nucleotide polymorphism rs7767652, which resides immediately upstream of the HCRTR2 gene, to identify individuals in need of treatment for heart failure who are predicted to be more responsive to medical intervention.