DERIVES DE 5-[4-(4-(2-AMINO-2-METHOXYCARBONYLETHYL)PHENOXY)BENZILIDENE] THIAZOLIDIN-2,4-DIONE ET COMPOSES ASSOCIES POUR LA REDUCTION DE NIVEAUX DE GLUCOSE, DE CHOLESTEROL ET DE TRIGLYCERIDES DANS LE PLASMA
Diphenyl ether compounds of the formula (I) are provided th-it exhibitactivity useful for reducing glucose, cholesterol, and/or triglyceride levelsin plasma, and for treatment of obesity, inflammation, immunological diseases,autoimmune diseases, diabetes and disorders associated with insulinresistance. (I) wherein represents an optional bond； W represents O or S； Zrepresents CR10, O or S； G represents O, S or together with R10 forms a 5 or 6membered aromatic or heteroaromatic ring system containing 1 or 2 heteroatomsselected from the group consisting of O, S and N； R8 represents OR13 orNR14R15； where R13 is selected from the group consisting of hydrogen,substituted and unsubstituted (C1-C20) alkyl, (C2-C20) alkenyl, (C5-C14) aryl,(C6-C34) aralkyl, (C1C13) heteroaryl, and a counter ion； and where R14 and R15are independently selected from the group consisting of H, substituted andunsubstituted (C1-C20) alkyl, (C2-C20) alkenyl and (C5-C14) aryl； the othersubstituents are defined in the claims.
