Utilisation de polypeptides dérivés de PEDF pour favoriser la prolifération de cellules souches et la cicatrisation des plaies

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专利权人:

Mackay Memorial Hospital

发明人:

申请号：

EP12160636.2

公开号：

EP2508196A1

申请日:

2012.03.21

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Disclosed herein is a synthetic peptide, which has an amino acid sequence that has 20-39 amino acid residues. The synthetic peptide has at least 80% amino acid sequence identity to SEQ ID NO: 1, and includes at least 20 consecutive residues that has at least 90% amino acid sequence identity to residues 11-30 of SEQ ID NO: 1. Also disclosed herein are compositions containing the synthetic peptide and applications thereof. According to various embodiments of the present disclosure, the synthetic peptide is useful in promoting stem cells proliferation or wound healing.

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