Imidazo bicyclic imminium compounds as antitumor agents

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专利权人:

The Board of Trustees of the Leland Stanford Junior University

发明人:

Chen, James,Kato, Tomoyo Sakata,Ondrus, Alison Evelynn

申请号：

AU2013277199

公开号：

AU2013277199A1

申请日:

2013.06.19

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

Imidazobicycles having a quaternary nitrogen, i.e. imminium salts, are disclosed. Examples include derivatives of 6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepinium and 2,3-dihydroimidazo[2,1-b]thiazolium salts. The compounds are inhibitors of the Hedgehog pathway and therefore useful as antitumor agents and as probes of the function of Hedgehog-dependent systems.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/