The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.本發明概言之係關於結合至NR1H4受體(FXR)且充當FXR之激動劑之化合物。本發明進一步係關於該等化合物用於製備用以透過該等化合物與該核受體之結合來治療疾病及/或病況之藥劑之用途;且關於合成該等化合物之方法。