METHOD OF APPLICATION OF COMBINATION OF DERIVATIVES OF BENZOPHENON OR ITS SALT AND IMMUNOSUPPRESSOR AND PHARMACEUTICAL COMPOSITION CONTAINING THESE COMPONENTS
1. A method of using a benzophenone derivative of the general formula [1] or a salt thereof and one or more immunosuppressants in combination for the treatment of autoimmune diseases! [Formula 1] ! ! where R1 represents a heterocycle that may be substituted, substituted phenyl or alkyl that may be substituted； Z represents alkylene which may be substituted； R2 represents a heterocycle that may be substituted, alkoxycarbonyl or a heterocyclic carbonyl that may be substituted, or a carboxyl that may be protected； R3 represents a hydrogen atom, a halogen atom, cyano, nitro, carboxyl which can be protected, hydroxyl which can be protected, amino which can be protected, mercapto, carbamoyl or alkyl, alkenyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy , acyl, alkoxycarbonyl, aryloxycarbonyl, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylamino, acylamino, alkylsulfonylamino, arylsulfonylamino or a heterocycle which may be substituted； R4 represents alkoxy, cycloalkyloxy, cycloalkenyloxy, alkyl, cycloalkyl, heterocycle-hydroxy or heterocycle, which may be substituted； and R5 represents a hydrogen atom, a halogen atom or hydroxyl. ! 2. The method according to claim 1, in which R1 represents a heterocycle that may be substituted, or substituted phenyl； R 2 is carboxyl which may be protected by an alkyl group； R3 is hydroxyl which may be protected； R4 is cycloalkyloxy which may be substituted； R5 represents a hydrogen atom； and Z is alkylene. ! 3. The method according to claim 1, in which R1 represents a heterocycle that may be substituted； R2 is carboxyl； and R3 represents g1. Способ применения производного бензофенона общей формулы [1] или его соли и одного или более иммуносупрессоров в комбинации для лечения аутоиммунных заболеваний ! [формула 1] ! ! где R1 представляет гетероцикл, который может быть замещен, замещенный фенил или алкил, который может быть замещен； Z представляет алкилен, который может быть замещен； R2 представляет гетероцикл, который может быть замеще
