Systems and methods for providing dialysis therapies are provided. In a general embodiment, the present disclosure provides an apparatus for dialysis treatment comprising first and second fluid flow pathways in a parallel arrangement. The first fluid flow pathway contains a first cation exchange resin, wherein greater than 90% of exchange sites of the first cation exchange resin are populated with hydrogen ions. The second fluid flow pathway contains a second cation exchange resin, wherein greater than 90% of exchange sites of the second cation exchange resin are populated with sodium ions. The apparatus can be used to maintain a constant and safe level of sodium in a constantly regenerated dialysis fluid over an extended period of time.本發明提供用於提供透析療法之系統及方法。在一般具體實例中,本發明提供包含呈平行配置之第一及第二流體流動路徑的透析處理之裝置。該第一流體流動路徑含有第一陽離子交換樹脂,其中該第一陽離子交換樹脂超過90%的交換位置係被氫離子佔據。該第二流體流動路徑含有第二陽離子交換樹脂,其中該第二陽離子交換樹脂超過90%的交換位置係被鈉離子佔據。該裝置可用於長期間使不斷再生之透析流體中維持恆定且安全之鈉含量。2‧‧‧透析系統4‧‧‧控制器10‧‧‧匣12‧‧‧入口14‧‧‧出口20‧‧‧第一管柱22‧‧‧第一陽離子交換樹脂30‧‧‧第二管柱32‧‧‧第二陽離子交換樹脂34‧‧‧障壁40‧‧‧脲酶層44,46‧‧‧入口表面積50‧‧‧氧化鋯層52,62‧‧‧可滲透層60‧‧‧碳層70‧‧‧來源72‧‧‧替代泵78‧‧‧泵80,82‧‧‧透析管線
