An endoscopic surgical cutting stapler (1) with a chain articulation comprises an end effector (2), a chain articulation (3), an extension tube (4), a stapler body (5) and an operating mechanism (6). The chain articulation (3) is composed of chain plates (24) and pivot pins (25). The chain articulation (3) is provided with a working channel extending from the proximal end to the distal end. A slide bar (8) passes through the working channel so as to execute the actions of the operating mechanism (6). The chain plates (24) are pivotally connected by the pivot pins (25) so as to form two staggered rows. The proximal end of the chain plate (24) at the most proximal end of the chain articulation (3) is driven by the operating mechanism (6), and the distal end has teeth. The other chain plates (24) of the chain articulation (3) have teeth at both ends, and the teeth of adjacent chain plates (24) in the same row engage with each other. The proximal end of the chain plate (24) at the most proximal end of the chain articulation (3) is pivotally connected with the extension tube (4). The distal end of the chain plate (24) at the most distal end of the chain articulation (3) is pivotally connected with the end effector (2). The distal end of the extension tube (4) has teeth. The teeth at the proximal end of the chain plate (24) at the sub-most proximal end of the chain articulation (3) mutually engage with the teeth at the distal end of the extension tube (4).Linvention porte sur une agrafeuse-coupeuse chirurgicale endoscopique (1) ayant une articulation à chaîne, laquelle agrafeuse-coupeuse comprend un effecteur terminal (2), une articulation à chaîne (3), un tube dextension (4), un corps dagrafeuse (5) et un mécanisme dactionnement (6). Larticulation à chaîne (3) est composée de plaques de chaîne (24) et de broches de pivotement (25). Larticulation à chaîne (3) comporte un canal de travail sétendant de lextrémité proximale à lextrémité distale. Une barre de coulissement (8)