Substituted Heterocyclic compounds with amide； Pharmaceutical composition, useful in the treatment of inflammatory or Autoimmune Disease.

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

MOSLIN RYAN M.,WEINSTEIN DAVID S.,WROBLESKI STEPHEN T.,TOKARSKI JOHN S.,KUMAR AMIT,BATT DOUGLAS G.,LIN SHUQUN,LIU CHUNJIAN,SPERGEL STEVEN H.,ZHANG YANLEI

申请号：

CL2015001231

公开号：

CL2015001231A1

申请日:

2015.05.07

申请国别(地区):

CL

年份:

2015

代理人:

摘要：

Compounds having the following formula I:or a stereoisomer or pharmaceutically-acceptable salt thereof, where R, R, R, R, and Rare as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.LA SOLICITUD SE REFIERE A COMPUESTOS DERIVADOS DE PIRIDAZINCARBOXAMIDA, MODULADORES DE IL-12, IL-23 Y/O IFNa QUE ACTÚAN EN TYK-2, UNA COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE Y A SU USO EN EL TRATAMIENTO ENFERMEDADES INFLAMATORIAS Y AUTOINMUNES

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/