利伯西利(RIBOCICLIB)錠劑农业专利-农业学术服务平台

发明人:: GURURAJAN, BINDHUMADHAVAN,古鲁拉杰　宾胡马哈分,古魯拉傑　賓胡馬哈分,GRANDEURY, ARNAUD,葛连德瑞　阿诺德,葛連德瑞　阿諾德,COSTA, RUI,柯斯塔　鲁伊,柯斯塔　魯伊,古鲁拉杰宾胡马哈分,古魯拉傑賓胡馬哈分,葛连德瑞阿诺德,葛連德瑞阿諾德,柯斯塔鲁伊,柯斯塔魯伊

摘要：: The present disclosure is directed to oral tablet of ribociclib including its salt(s). One embodiment of the present disclosure is directed to tablet of ribociclib with high drug load with an immediate release profile. One embodiment of the present disclosure is directed to coated tablet of ribociclib. Another embodiment of the present disclosure is directed to coated tablet of ribociclib where the coating is an advanced moisture barrier coating (e.g., Opadry® amb II coating where the coating is PVA based).本發明係關於包含利伯西利(ribociclib)或其鹽類的口服錠劑。本發明之一個實施例係關於具有高的載藥量與立即釋放曲線之利伯西利錠劑。本發明之一個實施例係關於利伯西利之經塗覆錠劑。本發明之另一實施例係關於利伯西利之經塗覆錠劑，其中塗料為先進的防潮塗料(例如，Opadry® amb II塗料，其中該塗料係以PVA為基礎)。