The present invention relates to a process for the preparation of 3 '- [(2Z) - [1- (3,4-dimethylphenyl) -1,5-dihydro- ] -2'-hydroxy- [1,1'-biphenyl] -3-carboxylic acid bis- (monoethanolamine) (elthrombopalloamine) and a process for the preparation thereof .Eltrombopakolamine, coordination metal, reducing sugar, thrombocytopenia, TPO receptor본 발명은 3'-[(2Z)-[1-(3,4-디메틸페닐)-1,5-디히드로-3-메틸-5-옥소-4H-피라졸-4-일리덴]히드라지노]-2'-히드록시-[1,1'-비페닐]-3-카르복실산 비스-(모노에탄올아민) (엘트롬보팍 올아민)을 함유하는 신규 제약 조성물 및 그의 제조 방법을 개시한다.